Fatty Acid Esterification and Chylomicron Formation during Fat Absorption in Rat. 3. Positional Relations in Triglycerides and Lecithin.

Fatty Acid Esterification and Chylomicron Formation during Fat Absorption. 1. Triglycerides and Cholesterol Esters.

Intestinal absorption and esterification of 14C-labeled fatty acids in man.

Investigations in which the lymph from the intestine has been collected have provided fundamental information on the subject of fat absorption (1, 2). In their classical studies on a patient with a lymph fistula, Munk and Rosenstein obtained good experimental evidence that fed triglycerides as well as free fatty acids are transported via the lymphatic pathway mainly as triglycerides (1). Since ...

Effects of palm oil and transesterified palm oil on chylomicron and VLDL triacylglycerol structures and postprandial lipid response.

The effects of positional distribution of triacylglycerol (TAG) fatty acids to TAG structures in chylomicrons and VLDL, and to postprandial lipemia, were studied in 10 healthy premenopausal women using a 6-h oral fat load test and a randomized, double-blind cross-over design. Molecular level information of TAG regioisomerism was obtained with a tandem mass spectrometric method. The positional d...

Chylomicron metabolism by the isolated perfused mouse heart.

The catabolism of rat chylomicrons, labeled in their triacylglycerol (TG) component, was investigated using perfused working mouse hearts. Perfusion of mouse hearts with heparin increased lipoprotein lipase (LPL) activity in the perfusate. This heparin-releasable LPL pool remained constant over a variety of experimental conditions, including workload and fatty acid concentrations, making the mo...

Direct esterification of monoglycerides with palmityl coenzyme A by intestinal epithelial subcellular fractions.

The attack of pancreatic lipase on ingested fats, which are mainly triglycerides, has been shown by Mattson et ~2. (l), Borgstrom (2), and Savary and Desnuelle (3) to be predominantly upon the ester linkages of the two primary alcohol groups of the glycerol molecule. This intraluminal intestinal hydrolysis results in preferential formation of monoglycerides, which display a marked tendency to a...